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美国国立卫生研究院T32外科研究人员研究培训的伦理问题

Ethics of research training for NIH T32 surgical investigators.

作者信息

Pollock R E, Curley S A, Lotzová E

机构信息

Department of Surgical Oncology, University of Texas M. D. Anderson Cancer Center, Houston 77030.

出版信息

J Surg Res. 1995 Feb;58(2):247-51. doi: 10.1006/jsre.1995.1038.

Abstract

As part of the revised curriculum of the NIH T32 Training Grant mechanism, 6 hr of formal instruction in ethics of research are now required. We therefore implemented a four-session seminar (6 hr total time) structured around assigned readings, didactic presentations, and group discussions. The objective of this research project was to assess whether this new program provided our trainees with a framework for ethical conduct in research. Twelve trainees completed the ethics course; 8 trainees who had not yet taken the ethics course served as a control group. All trainees answered a 72-item questionnaire of our own design that examined a variety of issues in research ethics. We compared the responses of seminar participant and nonparticipant groups using the Fisher exact test and Student t test for nominal and ordinal data, respectively. Both groups of trainees perceived that too much emphasis was placed on quantity rather than quality of publications. Both groups felt that this pressure emanated from department chairmen rather than laboratory mentors (P < 0.0001). In contrast to these shared perceptions, the two groups demonstrated many differences in their comprehension of research ethics. For example, compared to the controls, trainees who participated in the ethics course believed that they could define potential NIH standards for data storage and research mentorship (P < 0.05), understood gratuitous manuscript authorship (P < 0.05), were comfortable in dealing with outlier or discordant data (P < 0.10), and, most pertinently, were fully prepared to seek third-party input into an ethical dilemma involving their own work (P < 0.006).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

作为美国国立卫生研究院(NIH)T32培训资助机制修订课程的一部分,现在要求进行6小时的研究伦理正式教学。因此,我们开展了一个四场研讨会(总计6小时),围绕指定阅读材料、教学演示和小组讨论进行组织。本研究项目的目的是评估这个新项目是否为我们的学员提供了研究中的道德行为框架。12名学员完成了伦理课程;8名尚未参加伦理课程的学员作为对照组。所有学员都回答了一份我们自己设计的包含72个条目的问卷,该问卷考察了研究伦理中的各种问题。我们分别使用Fisher精确检验和Student t检验来比较研讨会参与者组和非参与者组对名义数据和有序数据的回答。两组学员都认为对出版物数量而非质量的强调过多。两组都觉得这种压力来自系主任而非实验室导师(P < 0.0001)。与这些共同看法形成对比的是,两组在对研究伦理的理解上表现出许多差异。例如,与对照组相比,参加伦理课程的学员认为他们能够定义潜在的NIH数据存储和研究指导标准(P < 0.05),理解无偿稿件作者身份(P < 0.05),能够自如处理异常值或不一致的数据(P < 0.10),最相关的是,他们完全准备好在涉及自己工作的伦理困境中寻求第三方的意见(P < 0.006)。(摘要截选至250字)

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