[Renal pathology in the Ivory Coast: exploration and functional activity of antithrombin iii].

Antithrombin III activity was determined in 96 ivorian adults clinically divided into 3 groups: I) nephrotic syndrome, II) chronic renal failure, and III) terminal uremia requiring maintenance dialysis. In the nephrotic syndrome, a significative decrease of antithrombin III is found, which can explain the existence of thrombotic complications. In chronic renal failure and terminal uremia, antithrombin III activity is normal, and thromboembolic events may be related to a deficiency of other inhibitors of the coagulation.