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长效镇静剂——医学实践中的一种替代方法(作者译)

[Long-term tranquilizers - an alternative in medical practice (author's transl)].

作者信息

Pach J, Waniek W

出版信息

Arzneimittelforschung. 1976;26(6):1189-90.

PMID:786318
Abstract

Over a period of 7 to 12 weeks we studied 3 series of 274 patients with depressive and somatic complaints treated with the long-acting neuroleptic fluspirilene in a dosage of 1-1.5 mg weekly. By means of various rating scales it was compared to diazepam in regard to its tranquilizing effects. Fluspirilene showed good activating and antidepressive qualities, which were superior to those of diazepam, whereas somatic complaints responded equally well to both drugs. The indications for a long-acting tranquilizer with the advantage of a controllable application are being discussed.

摘要

在7至12周的时间里,我们研究了3组共274例有抑郁和躯体不适症状的患者,他们接受了长效抗精神病药氟斯必林治疗,剂量为每周1 - 1.5毫克。通过各种评定量表,将其与地西泮的镇静效果进行了比较。氟斯必林显示出良好的振奋和抗抑郁特性,优于地西泮,而躯体不适症状对两种药物的反应相同。文中还讨论了具有可控应用优势的长效镇静剂的适应证。

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