剂量和场强对顺磁性造影剂增强效果的影响。
Effect of dose and field strength on enhancement with paramagnetic contrast media.
作者信息
Lindsey R O, Yetkin F Z, Prost R, Haughton V M
机构信息
Department of Radiology, Medical College of Wisconsin, Milwaukee 53226.
出版信息
AJNR Am J Neuroradiol. 1994 Nov;15(10):1849-52.
PURPOSE
To compare contrast enhancement per unit of dose of contrast medium in MR imaging at 0.5 and 1.5 T.
METHODS
Contrast enhancement in images made at 0.5 and 1.5 T after 0.1 mmol/kg of gadopentetate dimeglumine and 0.3 mmol/kg of gadodiamide was measured and the degree of contrast enhancement in the cavernous sinus and pituitary gland compared.
RESULTS
At both field strengths and both contrast medium doses, contrast enhancement was noted in the cavernous sinus, pituitary gland, infundibulum, maxillary sinus mucosa, falx cerebri, and choroid plexus on inspection of images. Enhancement was significantly and conspicuously less in the cavernous sinus and pituitary gland at 0.5 T (96% and 33%, respectively) than at 1.5 T (160% and 102%, respectively). No tissues were identified that enhanced only with the larger dose or higher field strength.
CONCLUSION
In tissues that normally enhance after intravenous administration of gadolinium chelates, enhancement is greater at 1.5 T than at 0.5 T.
目的
比较0.5T和1.5T磁共振成像中每单位剂量造影剂的对比增强情况。
方法
测量静脉注射0.1mmol/kg钆喷酸葡胺和0.3mmol/kg钆双胺后在0.5T和1.5T下所获图像的对比增强情况，并比较海绵窦和垂体的对比增强程度。
结果
在两种场强及两种造影剂剂量下，观察图像时均可见海绵窦、垂体、漏斗、上颌窦黏膜、大脑镰和脉络丛有对比增强。0.5T时海绵窦和垂体的增强明显低于1.5T（分别为96%和33%对比160%和102%）。未发现仅在较大剂量或较高场强下才增强的组织。
结论
在静脉注射钆螯合物后通常会增强的组织中，1.5T时的增强大于0.5T。
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