Deschamps M M, Johnson W D, Pape J W
Groupe Haitien D'Etude du Sarcome de Kaposi et des Infections Opportunistes (Gheskio), Port-au-Prince, Haiti.
AIDS Res Hum Retroviruses. 1994;10 Suppl 2:S231-3.
Human immunodeficiency virus (HIV) infection is spreading rapidly in Haiti with HIV seroprevalence rates of 10% and 3% in urban and rural areas, respectively. Since 1985, heterosexual transmission has been the primary mode of acquisition of HIV. From 1981 to the present, the Cornell-GHESKIO unit in Port-au-Prince, Haiti, has developed the infrastructure to recruit and retain large cohorts of individuals at risk for HIV infection. Among the populations studied, couples discordant for HIV infection appear most suitable for eventual HIV phase III vaccine trial. This paper describes the recruitment, retention, and characteristics of the discordant-couples cohort, as well as the limitations of interventions aimed at behavior modification.
人类免疫缺陷病毒（HIV）感染在海地迅速蔓延，城市和农村地区的HIV血清流行率分别为10%和3%。自1985年以来，异性传播一直是感染HIV的主要途径。从1981年至今，位于海地太子港的康奈尔 - 海地研究与培训协作组（Cornell - GHESKIO unit）已建立起相应基础设施，用于招募和留存大量有感染HIV风险的人群。在所研究的人群中，一方感染HIV而另一方未感染的夫妻似乎最适合最终的HIV三期疫苗试验。本文描述了一方感染而另一方未感染的夫妻队列的招募、留存情况及特征，以及旨在改变行为的干预措施的局限性。
