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海地的人类免疫缺陷病毒感染

Human immunodeficiency virus infection in Haiti.

作者信息

Pierre J A, Fournier A M

机构信息

University of Miami School of Medicine, FL, USA.

出版信息

J Natl Med Assoc. 1999 Mar;91(3):165-70.

Abstract

This article reviews human immunodeficiency virus (HIV) infection in Haiti. The evolution of the epidemic in Haiti, its spread from urban to rural areas, its varied clinical manifestations, and the attitudes of Haitian people toward HIV infection provide important lessons on understanding and managing this infection in a developing country. The heterosexual spread of HIV, particularly among the poor, is well-documented as is the role of other sexually transmitted diseases along with tuberculosis. Coinfection of HIV and tuberculosis have led researchers to study the effects of six-month supervised intermittent tuberculosis therapy both in controlling tuberculosis and slowing the progression of HIV. Various surveys and discussion groups about acquired immunodeficiency virus knowledge and beliefs demonstrate a large deficit in HIV education despite campaigns to educate the population. The great impact of HIV disease on morbidity and mortality in Haiti indicates that a great deal of work still needs to be accomplished and demonstrates the frustration in fighting the infection in countries with inadequate resources and infrastructure. Advances in HIV vaccine research seem to be the most promising option for developing countries such as Haiti.

摘要

本文回顾了海地的人类免疫缺陷病毒(HIV)感染情况。海地艾滋病疫情的演变、从城市到农村地区的传播、其多样的临床表现以及海地人民对HIV感染的态度,为在发展中国家理解和管理这种感染提供了重要经验教训。HIV的异性传播,尤其是在贫困人口中的传播,以及其他性传播疾病和结核病所起的作用都有充分记录。HIV与结核病的合并感染促使研究人员研究为期六个月的监督下间歇结核病治疗在控制结核病和减缓HIV进展方面的效果。尽管开展了针对民众的教育活动,但各种关于获得性免疫缺陷病毒知识和观念的调查及讨论小组表明,HIV教育仍存在很大不足。HIV疾病对海地发病率和死亡率的巨大影响表明,仍有大量工作需要完成,也显示出在资源和基础设施不足的国家抗击这种感染的挫败感。HIV疫苗研究的进展似乎是海地等发展中国家最有前景的选择。

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