Matsumoto T, Iida M, Kimura Y, Nanbu T, Fujishima M
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
J Gastroenterol Hepatol. 1994 Nov-Dec;9(6):572-5. doi: 10.1111/j.1440-1746.1994.tb01563.x.
The clinical, radiographic and endoscopic findings in 16 patients with ischaemic colitis, all of whom were < 45 years of age, were analysed. The clinical features were characterized by an acute onset of abdominal pain and rectal bleeding, and persistent constipation prior to the onset of symptoms. Twelve of the 16 patients did not have any known predisposing factors. Barium enema examination and colonoscopy revealed longitudinal ulcers and oedema of the left side of the colon of these patients. These features were then compared with those found in patients with ischaemic colitis, who were > 70 years of age. Although the clinical symptoms, the site of involvement and the initial radiographic or endoscopic findings were similar between the two groups, the transient form of ischaemic colitis and constipation prior to the onset of symptoms were more frequently present in the young patients than in the old patients. These findings suggest that ischaemic colitis, which is not a rare condition even in young adults, is less severe in young patients than in old patients, and that constipation may be related to the pathogenesis of this disease in young adults.
分析了16例缺血性结肠炎患者的临床、影像学和内镜检查结果，所有患者年龄均小于45岁。临床特征表现为腹痛和直肠出血急性发作，症状发作前持续便秘。16例患者中有12例无任何已知的诱发因素。钡剂灌肠检查和结肠镜检查显示这些患者结肠左侧有纵行溃疡和水肿。然后将这些特征与年龄大于70岁的缺血性结肠炎患者的特征进行比较。尽管两组患者的临床症状、受累部位以及初始影像学或内镜检查结果相似，但年轻患者中缺血性结肠炎的短暂形式和症状发作前的便秘比老年患者更常见。这些发现表明，缺血性结肠炎在年轻人中并非罕见疾病，年轻患者比老年患者病情较轻，并且便秘可能与年轻人这种疾病的发病机制有关。
