Hall J W, Walker I, Majak W
Agriculture Canada Research Station, Vancouver, British Columbia.
Can Vet J. 1994 Nov;35(11):702-5.
Poloxalene and a mineral mixture feed supplement patented for the treatment of emphysema, polyarthritis, and other pectin related diseases were tested in two trials for their ability to prevent bloat in cattle fed fresh alfalfa. Each trial had a crossover design using three Jersey steers with rumen fistulas per group. Each trial period continued until the total number of cases of bloat reached > or = 24. Treatments were given at 0800 each day. The mineral mixture was given at 100 g/d and 190 mg/kg body weight per day in the first and second trials, respectively. Poloxalene, which was tested only in the second trial, was given at 23 mg/kg body weight per day. Each group of steers was then fed 200 kg of freshly harvested alfalfa in the vegetative to early bloom stages of growth at 0830. In the first trial, only 69% as many cases of bloat occurred on the mineral mixture as on the control treatment, but no significant difference was detected in the second trial. The potency of the alfalfa may have been higher in the second trial, when forage dry matter was lower, magnesium and soluble nitrogen were higher, and bloat occasionally occurred twice a day. Bloat did not occur when the steers were treated with poloxalene. In these trials, poloxalene was completely effective in preventing bloat, but the mineral mixture was only partially so.
泊洛沙林和一种获得治疗肺气肿、多关节炎及其他与果胶相关疾病专利的矿物质混合饲料添加剂,针对其预防以新鲜苜蓿喂食的牛发生瘤胃胀的能力进行了两项试验。每项试验采用交叉设计,每组使用三头装有瘤胃瘘管的泽西种阉牛。每个试验期持续至瘤胃胀病例总数达到≥24例。每天08:00进行处理。在第一项和第二项试验中,矿物质混合物的给予量分别为每日100克和每千克体重190毫克。仅在第二项试验中进行测试的泊洛沙林,给予量为每千克体重每日23毫克。然后,每组阉牛在08:30时喂食200千克处于生长营养期至初花期的新鲜收获苜蓿。在第一项试验中,矿物质混合物组的瘤胃胀病例数仅为对照处理组的69%,但在第二项试验中未检测到显著差异。在第二项试验中苜蓿的效力可能更高,当时饲料干物质含量较低,镁和可溶性氮含量较高,且瘤胃胀偶尔一天发生两次。用泊洛沙林处理阉牛时未发生瘤胃胀。在这些试验中,泊洛沙林在预防瘤胃胀方面完全有效,但矿物质混合物仅部分有效。