Wennerholm K, Birkhed D, Emilson C G
Department of Cariology, Faculty of Odontology, Göteborg University, Sweden.
Caries Res. 1995;29(1):54-61. doi: 10.1159/000262041.
The effect of sugar restriction on the oral levels of mutans streptococci was studied in 20 subjects fulfilling three criteria: (1) having more than 300,000 CFU mutans streptococci/ml saliva, (2) harbouring both Streptococcus mutans and Streptococcus sobrinus in saliva, and (3) eating sugar frequently. The subjects were randomly divided into a test group (n = 12), who were asked to refrain from using sugar-containing foods between meals and to reduce sugar in main meals for 6 weeks, and a control group (n = 8), who did not receive any dietary advice. Saliva and plaque samples were collected at baseline and at 3, 6 and 12 weeks. The results showed that the levels of S. mutans and S. sobrinus decreased in saliva and plaque during the 6-week sugar restriction period. The decrese in mutans streptococci was more pronounced on buccal than on approximal tooth surfaces. Both species seemed to react in a similar way to the sugar restriction in saliva as well as in dental plaque. At the follow-up examination at 12 weeks, i.e. 6 weeks after completing the sugar restriction period, the numbers of S. mutans and S. sobrinus had increased again, but were still lower when compared to the baseline values.
在20名符合以下三条标准的受试者中研究了限制糖摄入对口腔变形链球菌水平的影响：（1）唾液中变形链球菌的菌落形成单位（CFU）超过300,000/ml，（2）唾液中同时存在变形链球菌和远缘链球菌，（3）经常食用糖。受试者被随机分为试验组（n = 12），要求他们在两餐之间避免食用含糖食物，并在6周内减少主餐中的糖摄入量；以及对照组（n = 8），不接受任何饮食建议。在基线以及第3、6和12周采集唾液和牙菌斑样本。结果显示，在为期6周的糖限制期内，唾液和牙菌斑中变形链球菌和远缘链球菌的水平下降。变形链球菌在颊面的减少比邻面更明显。这两种菌在唾液和牙菌斑中对糖限制的反应似乎相似。在12周的随访检查中，即在完成糖限制期6周后，变形链球菌和远缘链球菌的数量再次增加，但与基线值相比仍较低。
