Taylor M A, Amir N
Department of Psychiatry and Behavioral Sciences, Finch University of Health Sciences/Chicago Medical School, North, IL 60064.
Compr Psychiatry. 1994 Nov-Dec;35(6):420-9. doi: 10.1016/0010-440x(94)90224-0.
Schizophrenia and affective disorder are separately classified. Schizoaffective disorder has been considered a variant of these, or representing several diseases. Some hypothesize a psychosis continuum. One test of these contrasting views involves discriminating the psychoses by their classic symptoms. We used discriminant function analyses to assess the ability of systematically recorded psychopathology to distinguish 167 DSM-III schizophrenics from 74 affectives. We divided the schizophrenics into chronic and schizoaffective subgroups. We discriminated chronic schizophrenics from affectives, but schizoaffectives overlapped both groups. Schizoaffective/unipolars were like chronic schizophrenics, and schizoaffective/bipolars were like affectives. However, these discriminations also substantially overlapped, and among non-affective positive features formal thought disorder was best at discrimination. Our findings do not fully support the present classification system, and suggest that its emphasis on hallucinations and delusions is overvalued.
精神分裂症和情感障碍被分别分类。分裂情感性障碍曾被认为是这些疾病的一种变体，或者代表几种疾病。一些人假设存在精神病连续体。对这些不同观点的一个检验涉及通过经典症状来区分精神病。我们使用判别函数分析来评估系统记录的精神病理学特征区分167名DSM-III精神分裂症患者和74名情感障碍患者的能力。我们将精神分裂症患者分为慢性组和分裂情感性障碍亚组。我们能够区分慢性精神分裂症患者和情感障碍患者，但分裂情感性障碍患者与两组都有重叠。分裂情感性障碍/单相情感障碍患者类似慢性精神分裂症患者，而分裂情感性障碍/双相情感障碍患者类似情感障碍患者。然而，这些区分也有很大重叠，在非情感性阳性特征中，形式思维障碍在区分方面表现最佳。我们的研究结果并不完全支持当前的分类系统，并表明其对幻觉和妄想的强调被高估了。
