Jain R, Isaac R M, Gottschalk M E, Myers T F
Department of Pediatrics, Loyola University Chicago, Stritch School of Medicine, Maywood, IL.
J Endocrinol Invest. 1994 Sep;17(8):631-4. doi: 10.1007/BF03349676.
The course of two neonates and one 4-month-old infant with laboratory and clinical evidence of central hypothyroidism is described. All three presented with failure to thrive and improved after L-T4 therapy. Early recognition and treatment of newborns and infants with central hypothyroidism is important to maximize the potential for growth and development. Two of the three infants have been documented to have transient central hypothyroidism of hypothalamic origin, not previously reported.
描述了两名新生儿和一名4个月大婴儿出现中枢性甲状腺功能减退的实验室及临床证据的病程。这三名患儿均表现为生长发育迟缓，在接受左甲状腺素（L-T4）治疗后症状改善。对新生儿和婴儿中枢性甲状腺功能减退进行早期识别和治疗，对于最大化生长发育潜力非常重要。这三名婴儿中有两名被记录为下丘脑起源的暂时性中枢性甲状腺功能减退，此前未见报道。
