Limthongkul S, Charoenlap P, Wongthim S, Udompanich V, Nuchprayoon C
Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
J Med Assoc Thai. 1994 May;77(5):225-30.
One hundred and forty three among five hundred and twenty-six cases of bacterial pneumonia in adults (27.2%) who had pleural effusion (parapneumonic effusion) admitted to Chulalongkorn Hospital during the period January 1987 to December 1991 were analyzed. There were 40 cases with effusion that was less than 10 mm thick on chest decubitus film, 44 cases of uncomplicated exudative phase, 40 cases of complicated exudative phase (early empyema) and 19 cases of empyema. Most patients in our study required thoracocentesis (72%), had early empyema and emyema (41.3%) as well as high incidence of positive organisms on Gram stain in pleural fluid. This indicates that our patients may have had a prolonged clinical course before coming to the hospital. About half of our patients had pleuitic chest pain or signs of pleural effusion. Among the various stages of parapneumonic effusion, the empyema group had the most delayed response to treatment and needed intercostal drainage for twice the duration of the early empyema group (15.69 vs 7.55 days). The overall mortality was 22.4 per cent. Factors associated with death were advanced age, hospital acquired and broncho-pneumonia, abnormal host, no pleuritic chest pain, no signs of consolidation, respiratory failure, shock and complications of assisted ventilation.
对1987年1月至1991年12月期间朱拉隆功医院收治的526例成人细菌性肺炎合并胸腔积液(肺炎旁胸腔积液)患者中的143例(27.2%)进行了分析。其中,40例患者胸腔积液在胸部侧卧位片上厚度小于10mm,44例处于单纯渗出期,40例处于复杂渗出期(早期脓胸),19例为脓胸。本研究中的大多数患者需要胸腔穿刺术(72%),存在早期脓胸和脓胸(41.3%),且胸腔积液革兰氏染色阳性菌的发生率较高。这表明我们的患者在入院前可能有较长的临床病程。约一半的患者有胸膜炎性胸痛或胸腔积液体征。在肺炎旁胸腔积液的各个阶段中,脓胸组对治疗的反应最延迟,肋间引流所需时间是早期脓胸组的两倍(15.69天对7.55天)。总死亡率为22.4%。与死亡相关的因素包括高龄、医院获得性肺炎和支气管肺炎、宿主异常、无胸膜炎性胸痛、无实变体征、呼吸衰竭、休克以及辅助通气并发症。