Lauzon P, Vincelette J, Bruneau J, Lamothe F, Lachance N, Brabant M, Soto J
Detoxification Unit, Hôpital Saint-Luc, Montreal, Quebec, Canada.
J Subst Abuse Treat. 1994 Sep-Oct;11(5):457-61. doi: 10.1016/0740-5472(94)90099-x.
Few studies have been done on the prevalence of illicit methadone use. Five hundred fifty-nine IV drug users recruited in various ways in Montreal were interviewed concerning their drug use as part of a longitudinal study on HIV infection. Of this number, 133 had heroin as their drug of preference and 426 cocaine. Among the cocaine group, 202 also used heroin. The lifetime prevalence of any illicit methadone use was 59.4% in the heroin group, 26.7% in the cocaine/heroin group, and 3.6% in the cocaine-only group. The 6-month (preceding the interview) prevalence of any illicit use was 42.1%, 6.9%, and 1.3%, respectively, and the prevalence of at least weekly illicit use during that period was 6.3%, 2.0%, and 0%, respectively. The prevalence of illicit methadone use is significant in the population studied. Whether this level of use will be affected by more stringent control on methadone prescription and dispensation remains to be demonstrated.
关于非法使用美沙酮的流行情况,所开展的研究较少。作为一项关于艾滋病毒感染的纵向研究的一部分,对在蒙特利尔通过各种方式招募的559名静脉注射吸毒者进行了有关其吸毒情况的访谈。在这些人中,133人首选海洛因,426人首选可卡因。在可卡因组中,有202人也使用海洛因。在海洛因组中,曾非法使用过美沙酮的终生患病率为59.4%,在可卡因/海洛因组中为26.7%,在仅使用可卡因组中为3.6%。在接受访谈前6个月内,曾非法使用过美沙酮的患病率分别为42.1%、6.9%和1.3%,在此期间至少每周非法使用的患病率分别为6.3%、2.0%和0%。在所研究的人群中,非法使用美沙酮的情况较为显著。美沙酮处方和配给方面更严格的管控是否会影响这种使用水平,仍有待证实。