Bux D A, Lamb R J, Iguchi M Y
Medical College of Pennsylvania, Department of Psychiatry, Philadelphia.
Drug Alcohol Depend. 1995 Jan;37(1):29-35. doi: 10.1016/0376-8716(94)01058-s.
This study examined sexual and drug use behavior in 247 methadone maintenance patients, to explore the association of cocaine use with human immunodeficiency virus (HIV) risk behavior. In univariate analyses, cocaine use was positively associated with any drug injection, number of injections, and sexual intercourse without condoms. These relationships remained significant after controlling for other drug use and demographic factors. Heroin use also contributed to injection-related risk. We conclude that cocaine use represents a continued source of risk for exposure to HIV in this population, and that more aggressive efforts are warranted to reduce illicit drug use, particularly of heroin and cocaine, in methadone patients.
本研究调查了247名美沙酮维持治疗患者的性行为和药物使用行为，以探讨可卡因使用与人类免疫缺陷病毒（HIV）风险行为之间的关联。在单变量分析中，可卡因使用与任何药物注射、注射次数以及无保护措施的性行为呈正相关。在控制了其他药物使用和人口统计学因素后，这些关系仍然显著。海洛因使用也增加了与注射相关的风险。我们得出结论，在这一人群中，可卡因使用仍是感染HIV的持续风险来源，因此有必要采取更积极的措施来减少美沙酮治疗患者的非法药物使用，尤其是海洛因和可卡因的使用。
