1985 - 1989年荷兰阿姆斯特丹注射吸毒者中使用海洛因和可卡因情况随时间的变化。

Changes over time in heroin and cocaine use among injecting drug users in Amsterdam, The Netherlands, 1985-1989.

作者信息

Hartgers C, Van den Hoek A, Krijnen P, Van Brussel G H, Coutinho R A

机构信息

Municipal Health Service, Department of Public Health and Environment, Amsterdam, The Netherlands.

出版信息

Br J Addict. 1991 Sep;86(9):1091-7. doi: 10.1111/j.1360-0443.1991.tb01876.x.

DOI:10.1111/j.1360-0443.1991.tb01876.x

PMID:1932880

Abstract

Three hundred and eighty six injecting drug users entered into an HIV study through methadone programs over a 40 month period. Differences in oral, intranasal and parenteral use of heroin and cocaine were assessed between four consecutive 10 month intake groups. Heroin smoking and cocaine freebasing were increased in the later intake groups, while there were no significant changes in injecting variables. No relationship between sexual risk behaviour and cocaine freebasing was found. HIV seropositivity was less among cocaine freebasers at 19% compared to 32% among non freebasers. The increase in heroin smoking and cocaine freebasing may have a favourable preventive effect on the spread of HIV among this high risk group.

摘要

在40个月的时间里，386名注射吸毒者通过美沙酮项目参与了一项艾滋病病毒研究。对连续四个10个月入组的人群评估了海洛因和可卡因在口服、鼻吸及注射使用方面的差异。在后期入组人群中，吸食海洛因和抽可卡因的情况有所增加，而注射变量方面无显著变化。未发现性风险行为与抽可卡因之间存在关联。抽可卡因者的艾滋病毒血清阳性率为19%，低于非抽可卡因者的32%。吸食海洛因和抽可卡因情况的增加可能对艾滋病病毒在这一高危群体中的传播具有有利的预防作用。