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阿糖胞苷诱导的心包炎:一例病例报告及阿糖胞苷治疗心肺并发症的文献综述

Cytarabine-induced pericarditis: a case report and review of the literature of the cardio-pulmonary complications of cytarabine therapy.

作者信息

Reykdal S, Sham R, Kouides P

机构信息

Department of Medicine, Rochester General Hospital, NY 14621.

出版信息

Leuk Res. 1995 Feb;19(2):141-4. doi: 10.1016/0145-2126(94)00123-r.

DOI:10.1016/0145-2126(94)00123-r
PMID:7869742
Abstract

Pericarditis is a rare complication of chemotherapy. This report describes a patient who developed symptoms, signs, and electrocardiographic evidence of pericarditis following treatment with high dose cytarabine. The patient had no clinical or echocardiographic evidence of infection or leukemic involvement of the pericardium. Isolated pericarditis associated with high dose cytarabine has been rarely reported. This therapy is frequently used and, therefore, it seems prudent to alert physicians to this potential complication of cytarabine. The cardiopulmonary complications of cytarabine are also reviewed.

摘要

心包炎是化疗的一种罕见并发症。本报告描述了一名患者,在接受大剂量阿糖胞苷治疗后出现了心包炎的症状、体征及心电图证据。该患者没有感染或白血病累及心包的临床或超声心动图证据。与大剂量阿糖胞苷相关的孤立性心包炎鲜有报道。这种治疗方法经常使用,因此,提醒医生注意阿糖胞苷的这一潜在并发症似乎是谨慎之举。同时也对阿糖胞苷的心肺并发症进行了综述。

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