Ettinger W H, Afable R F
Department of Internal Medicine, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157-1051.
Med Sci Sports Exerc. 1994 Dec;26(12):1435-40.
Osteoarthritis (OA) of the knee is a common, nonfatal, chronic condition that causes pain and physical disability in older people. Persons with knee OA report difficulty with activities that require ambulation and transfer from the sitting to the standing position. Physical disability from knee OA is the result of a complex interplay among the severity of disease, pain, comorbid conditions, psychosocial factors, and deficits in physical capacity such as low aerobic work capacity and lower extremity muscle weakness. These deficits in physical capacity may be correctable with exercise training. Short-term studies indicate that persons with knee OA show gains in physical capacity and report less pain and disability with exercise training. However, the long-term effectiveness and safety of exercise in persons with knee OA remains unknown.
膝关节骨关节炎（OA）是一种常见的、非致命的慢性疾病，会导致老年人疼痛和身体残疾。膝关节OA患者报告称，在需要行走以及从坐姿转换为站立姿势的活动中存在困难。膝关节OA导致的身体残疾是疾病严重程度、疼痛、合并症、心理社会因素以及身体能力缺陷（如低有氧工作能力和下肢肌肉无力）之间复杂相互作用的结果。这些身体能力缺陷可能通过运动训练得到改善。短期研究表明，膝关节OA患者通过运动训练后身体能力有所提高，疼痛和残疾情况也有所减轻。然而，运动对膝关节OA患者的长期有效性和安全性仍然未知。
