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最常处方药物的口腔副作用。

Oral side-effects of the most frequently prescribed drugs.

作者信息

Smith R G, Burtner A P

机构信息

Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville.

出版信息

Spec Care Dentist. 1994 May-Jun;14(3):96-102. doi: 10.1111/j.1754-4505.1994.tb01112.x.

Abstract

Oral side-effects and their respective prevalence rates for the 200 most frequently prescribed drugs for 1992, as measured by IMS America's National Prescription Audit is reviewed. Accounting for duplication due to brand and generic name listings, the actual number of different medications covered was 131. The results of this review are presented in a table and include the oral side-effects and prevalences as reported in the literature. The three most frequent side-effects encountered with these medications were xerostomia (80.5%), dysgeusia (47.5%), and stomatitis (33.9%). The included table should fill the need for a ready reference for dentists in monitoring and counseling patients regarding the potential oral side-effects of the medications.

摘要

本文回顾了1992年通过IMS美国国家处方审计所测定的200种最常用处方药的口腔副作用及其各自的发生率。由于品牌名和通用名列表存在重复,实际涵盖的不同药物数量为131种。本次回顾的结果以表格形式呈现,其中包括文献报道的口腔副作用及发生率。这些药物最常出现的三种副作用是口干(80.5%)、味觉障碍(47.5%)和口腔炎(33.9%)。所附表格应能满足牙医在监测和咨询患者有关药物潜在口腔副作用方面随时查阅的需求。

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