Garcia H H, Gilman R H, Tovar M A, Flores E, Jo R, Tsang V C, Diaz F, Torres P, Miranda E
Laboratorio de Parasitologia, Universidad Peruana Cayetano Heredia, Lima.
Am J Trop Med Hyg. 1995 Feb;52(2):145-8. doi: 10.4269/ajtmh.1995.52.145.
In most developing countries, 10% of acute neurologic cases are patients with neurocysticercosis (NCC). Determining specific factors associated with contracting NCC will facilitate its diagnosis and prevention. We examined multiple socioeconomic, demographic, environmental, medical, and behavioral characteristics of 946 Peruvian neurologic patients for a correlation with NCC, which was diagnosed by the highly specific and sensitive electroimmunotransfer blot (EITB) or immunoblot assay. Eighteen percent (172 of 932) of serum samples and 28% (101 of 362) of cerebrospinal fluid samples were EITB-positive. The proportion of EITB-positive persons was similar for all socioeconomic levels. Significant factors associated with NCC were: 1) being born outside Lima, 2) having raised pigs, 3) more than 20 years of age, 4) a history of seizures, and 5) a history of taeniasis. Of these factors, raising pigs is the only one that is amenable to intervention, via improvements in animal husbandry.
在大多数发展中国家，10%的急性神经病例是患有神经囊尾蚴病（NCC）的患者。确定与感染NCC相关的具体因素将有助于其诊断和预防。我们检查了946名秘鲁神经科患者的多种社会经济、人口统计学、环境、医学和行为特征，以寻找与NCC的相关性，NCC通过高度特异性和敏感性的电免疫转移印迹法（EITB）或免疫印迹测定法进行诊断。18%（932份血清样本中的172份）的血清样本和28%（362份脑脊液样本中的101份）的脑脊液样本EITB呈阳性。所有社会经济水平的EITB阳性者比例相似。与NCC相关的显著因素有：1）出生在利马以外，2）饲养过猪，3）年龄超过20岁，4）有癫痫发作史，5）有绦虫病史。在这些因素中，饲养猪是唯一可以通过改善畜牧业进行干预的因素。
