Marcillon M
Département d'Anesthésie-Réanimation, CHU de Nice, Hôpital Saint-Roch.
Ann Fr Anesth Reanim. 1994;13(4):529-32. doi: 10.1016/S0750-7658(05)80689-6.
Irrespective of the type of surgery, patient monitoring, including ECG-automated non-invasive blood pressure measurements, SpO2, FIO2 and capnography, is compulsory. Sedation: no initial bolus injection of propofol; continuous infusion of propofol at a rate of 1 to 4 mg.kg-1.h-1, using a syringe pump, combined with a short-acting opioid such as alfentanil. General anaesthesia: initial bolus injection of propofol between 2 and 3.5 mg.kg-1, combined with 10 mg of lidocaine in the same syringe; maintenance with a syringe pump: 6 to 9 mg.kg-1.h-1 combined with an opioid, with or without coadministration of muscle relaxants. Intubation avoiding respiratory depression: syringe pump with a fast infusion rate (50 to 100 mg.min-1), which allows induction with propofol and intubation without co-administration of muscle relaxants.
无论手术类型如何，患者监测（包括心电图、自动无创血压测量、脉搏血氧饱和度、吸入氧分数和二氧化碳描记法）都是必需的。镇静：不进行丙泊酚初始推注；使用注射泵以1至4mg·kg⁻¹·h⁻¹的速率持续输注丙泊酚，并联合使用短效阿片类药物如阿芬太尼。全身麻醉：丙泊酚初始推注剂量为2至3.5mg·kg⁻¹，同一注射器中加入10mg利多卡因；使用注射泵维持：6至9mg·kg⁻¹·h⁻¹并联合阿片类药物，可加用或不加用肌肉松弛剂。避免呼吸抑制的插管：使用快速输注速率（50至100mg·min⁻¹）的注射泵，可在不联合使用肌肉松弛剂的情况下用丙泊酚诱导并插管。
