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[硬膜外刺激治疗难治性心绞痛]

[Epidural stimulation in the treatment of refractory angina].

作者信息

Jacques L, Napoléon Martinez S, Gagnon R M, Savard D, René D

机构信息

Service de Neurologie, Hôpital Notre-Dame, Université de Montréal, Québec, Canada.

出版信息

Ann Chir. 1994;48(8):764-7.

PMID:7872628
Abstract

Twelve patients with refractory angina pectoris previously treated with angioplasty or coronary bypass and under optimal medical therapy were treated with spinal cord electrical stimulation (SCES) at the C7 to D2 level since 1988. Six patients had a significant improvement of symptoms confirmed by a reduced incidence of chest pain and decreased used of nitroglycerin. Three patients required removal of electrode (heart transplantation, inadequate comprehension and foreign body reaction). These patients did however benefit from the effect of SCES for sometimes. Three patients died. The SCES may improve the quality of life by reducing the incidence of chest pain in patients previously uncontrolled with maximal medical and surgical therapy.

摘要

自1988年以来,12例曾接受过血管成形术或冠状动脉搭桥手术且处于最佳药物治疗下的难治性心绞痛患者,在C7至D2水平接受了脊髓电刺激(SCES)治疗。6例患者症状有显著改善,胸痛发生率降低和硝酸甘油使用量减少证实了这一点。3例患者需要移除电极(心脏移植、理解能力不足和异物反应)。不过这些患者在一段时间内确实从SCES的效果中获益。3例患者死亡。对于那些曾接受最大程度药物和手术治疗仍无法控制病情的患者,SCES可能通过降低胸痛发生率来改善生活质量。

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