Kerslake R W, Fox J N, Carleton P J, Imrie M J, Cook A M, Bowsley S J, Horsman A
Centre for Magnetic Resonance Investigations, Hull Royal Infirmary, UK.
Br J Radiol. 1994 Dec;67(804):1158-68. doi: 10.1259/0007-1285-67-804-1158.
20 women with suspected recurrent breast cancer who had undergone previous breast-conserving operations were investigated using dynamic contrast-enhanced gradient echo (GRE) and fat suppressed spin echo (SE) magnetic resonance (MR) imaging. Histologically confirmed recurrent tumour was readily recognized on dynamic GRE scans by virtue of rapid, early and avid enhancement. Benign scars enhanced more slowly and reached lower magnitudes of enhancement. Fat suppressed SE images, which were typically acquired 10 min after contrast administration, were sensitive for the detection of tumour recurrence but lacked specificity. Early scanning after contrast administration offers the best prospects for distinguishing tumour recurrence from benign scarring. The criteria used to distinguish these two entities are highly dependent on the scan technique and the time at which images are obtained post-contrast.
对20名曾接受保乳手术且疑似复发性乳腺癌的女性，采用动态对比增强梯度回波（GRE）和脂肪抑制自旋回波（SE）磁共振（MR）成像进行研究。组织学确诊的复发性肿瘤在动态GRE扫描中很容易被识别，因其具有快速、早期且强烈的强化表现。良性瘢痕强化较慢，强化程度较低。脂肪抑制SE图像通常在注射造影剂10分钟后采集，对肿瘤复发的检测很敏感，但缺乏特异性。注射造影剂后早期扫描最有助于区分肿瘤复发和良性瘢痕。用于区分这两种情况的标准高度依赖于扫描技术以及造影剂注射后图像的采集时间。
