Cohen E K, Leonhardt C M, Shumak R S, Soutar I C, Bukhanov K, Fishell E K, Plewes D B
Department of Radiology, Mount Sinai Hospital, Toronto, Ontario.
Can Assoc Radiol J. 1996 Jun;47(3):171-6.
To determine the sensitivity and specificity of magnetic resonance imaging (MRI) of the breast for detecting recurrent carcinoma.
Thirteen patients ranging in age from 47 to 77 years who had undergone lumpectomy 5 months to 8 years earlier and who had mammographic findings suggestive of recurrence underwent contrast-enhanced dynamic MRI. Histologic confirmation was obtained in all cases.
Of the eight lesions (in seven patients) for which biopsy proved recurrence, MRI correctly identified six; there were two false negative results. Of the six benign lesions, four were correctly identified by MRI. The two false positive results involved fat necrosis and a foreign-body reaction respectively.
These results confirm previous reports of the poor specificity of MRI of focal breast lesions. The authors therefore recommend caution in the use of breast MRI in the assessment and management of suspected recurrent carcinoma.
确定乳腺磁共振成像（MRI）检测复发性癌的敏感性和特异性。
13例年龄在47至77岁之间的患者，这些患者在5个月至8年前接受了肿块切除术，乳房X线摄影结果提示复发，随后接受了对比增强动态MRI检查。所有病例均获得了组织学证实。
在活检证实为复发的8个病灶（7例患者）中，MRI正确识别出6个；有2例假阴性结果。在6个良性病灶中，MRI正确识别出4个。2例假阳性结果分别涉及脂肪坏死和异物反应。
这些结果证实了先前关于乳腺局灶性病变MRI特异性较差的报道。因此，作者建议在评估和处理疑似复发性癌时谨慎使用乳腺MRI。
