Boné B, Aspelin P, Isberg B, Perbeck L, Veress B
Department of Diagnostic Radiology, Karolinska Institute, Huddinge Hospital, Sweden.
Acta Radiol. 1995 Mar;36(2):111-6.
The purpose of the study was to determine the value of contrast-enhanced MR imaging in the assessment of local recurrence in breast cancer patients who underwent mastectomy and breast reconstruction with an implant. Eighty-three patients have been evaluated by semidynamic contrast-enhanced MR imaging. The T1-weighted FLASH 3-D sequence was repeated twice postcontrast for evaluation of the entire breast bilaterally. The findings were compared to physical examination, mammography and histopathology. Recurrence verified by histopathology occurred in 14 of 83 patients (17%). Contrast-enhanced MR imaging was superior to palpation and mammography in revealing recurrences, especially when these were located close to the chest wall. MR was also more sensitive in detecting multiple foci of cancers. Our study revealed that MR imaging was influenced by size, type and composition of the tumor, as illustrated by the false-negative results. Therefore, the use of all 3 investigation methods is necessary for detecting recurrence at an early stage during the postoperative follow-up.
本研究的目的是确定对比增强磁共振成像在评估接受乳房切除术及植入物乳房重建的乳腺癌患者局部复发情况中的价值。83例患者接受了半动态对比增强磁共振成像评估。在注射造影剂后，采用T1加权快速小角度激发三维序列对双侧整个乳房重复扫描两次以进行评估。将检查结果与体格检查、乳房X线摄影及组织病理学结果进行比较。经组织病理学证实，83例患者中有14例（17%）出现复发。在发现复发方面，对比增强磁共振成像优于触诊和乳房X线摄影，尤其是当复发灶位于靠近胸壁处时。磁共振成像在检测多个癌灶方面也更敏感。我们的研究表明，磁共振成像受肿瘤大小、类型及成分的影响，这表现为出现假阴性结果。因此，在术后随访期间，为早期发现复发，三种检查方法都有必要使用。
