Hui Z, Zhao Z, Zhang L
Huhehaote Hygiene and Epidemic Prevention Station.
Zhonghua Liu Xing Bing Xue Za Zhi. 1994 Dec;15(6):351-3.
Three serologic markers for screening before hepatitis B vaccination were HBsAg, anti-HBs and anti-HBc. The data of HB virus infection in eight cities were analysed in order to save test cost and to achieve similar immune effect. For routine screening, anti-HBc is the only one marker needed to be used. The neonates and children aged 0-3 years can be vaccinated directly without screening.
乙肝疫苗接种前用于筛查的三项血清学标志物是乙肝表面抗原(HBsAg)、乙肝表面抗体(抗-HBs)和乙肝核心抗体(抗-HBc)。为节省检测成本并达到相似的免疫效果,对八个城市的乙肝病毒感染数据进行了分析。对于常规筛查,抗-HBc是唯一需要使用的标志物。新生儿和0至3岁儿童无需筛查可直接接种疫苗。