Heyer G, Berg P, Hornstein O P
Dermatologische Universitätsklinik, Erlangen.
Hautarzt. 1995 Jan;46(1):22-7. doi: 10.1007/s001050050202.
In atopic eczema patients the well-known abnormal cutaneous reactivity of the blood vessels (white dermographism, delayed blanch after acetylcholine, paradoxical blanching after nicotinic acid application and diminished erythema after histamine injection) were observed during acute eczematous episodes and later in an exzema-free state in comparison with controls. In this follow-up study the use of different stimuli allowed us to demonstrate abnormal cutaneous vascular reactions in the patients depending on the severity of their atopic eczema. Severely affected patients showed persistence of the paradoxical vascular reactions even in an eczema-free cutaneous state.
在特应性皮炎患者中,在急性湿疹发作期间以及之后处于无湿疹状态时,与对照组相比,观察到了众所周知的血管皮肤反应异常(白色皮肤划痕症、乙酰胆碱后延迟苍白、应用烟酸后反常苍白以及注射组胺后红斑减弱)。在这项随访研究中,使用不同的刺激使我们能够证明患者的皮肤血管反应异常取决于其特应性皮炎的严重程度。即使在皮肤无湿疹状态下,重度受累患者仍表现出反常血管反应持续存在。