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[犬模型中膝关节血管化自体和同种异体移植的手术技术]

[Surgical technique in vascularized auto- and allotransplantation of the knee joint in a dog model].

作者信息

Fricker R, Schäfer D, Rosso R, Lüscher U, Schläpfer R, Filguera L, Brennwald J, Landmann J, Regazzoni P, Heberer M

机构信息

Allgemeinchirurgische Klinik, Kantonsspital Basel.

出版信息

Helv Chir Acta. 1994 Dec;60(6):1015-9.

PMID:7875978
Abstract

Experimental transplantation of vascularized canine knee joints has so far been associated with high complication rates in both auto- and allografts. We have now compared 4 autografts and 4 allografts that were successfully performed at our institution. This report details our surgical technique. Stable internal fixation enabling immediate postoperative weight bearing, microsurgical end-to-end anastomoses of popliteal artery and vein and postoperative control of immunosuppression in transplanted animals are crucial. Thus, an interdisciplinary approach of experts in microsurgery, orthopedic and trauma surgery and immunologists appears to be a prerequisite for successful joint transplantation.

摘要

迄今为止,带血管的犬膝关节实验性移植在自体移植和同种异体移植中均伴有高并发症发生率。我们现已比较了在本机构成功实施的4例自体移植和4例同种异体移植。本报告详细介绍了我们的手术技术。稳定的内固定使术后能立即负重、腘动脉和腘静脉的显微外科端端吻合以及对移植动物术后免疫抑制的控制至关重要。因此,显微外科、骨科与创伤外科专家以及免疫学家的跨学科方法似乎是关节移植成功的先决条件。

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