Otsuka Y, Kitamura S, Arimura T, Misawa S, Oguri T, Shimada K
Clinical Laboratories, Juntendo University Hospital.
Kansenshogaku Zasshi. 1994 Dec;68(12):1527-32. doi: 10.11150/kansenshogakuzasshi1970.68.1527.
We report a case of Corynebacterium jeikeium septicemia associated with malignant lymphoma. The patient is a 58-year-old male who was diagnosed as malignant lymphoma on August 1992. May 15, 1993, he was admitted to our hospital because of oliguria, abdominal flatulence and vomiting which developed a few days before admission. Anticancer regimen were started. In the middle of July, white blood cell (WBC) count dropped to 100/mm3 and body temperature rose to 39 degrees C. He was been treated with Ceftazidime and Piperacillin. C. jeikeium was recovered from blood culture. Antibiotics were switched to minocycline and vancomycin. He died of septic shock and pneumonia. Autopsy revealed the presence of the colonies of Rods. Which were morphologically compatible with C. jeikeium were observed in lung tissue and in the small pulmonary vessels.
我们报告一例与恶性淋巴瘤相关的杰氏棒状杆菌败血症病例。患者为一名58岁男性，于1992年8月被诊断为恶性淋巴瘤。1993年5月15日，因入院前几天出现少尿、腹胀和呕吐而入住我院。开始了抗癌治疗方案。7月中旬，白细胞计数降至100/mm³，体温升至39℃。他接受了头孢他啶和哌拉西林治疗。血培养分离出杰氏棒状杆菌。抗生素更换为米诺环素和万古霉素。他死于感染性休克和肺炎。尸检显示存在杆状菌落。在肺组织和肺小血管中观察到形态上与杰氏棒状杆菌相符的菌落。
