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M2/t(8; 21)急性非淋巴细胞白血病的形态学研究

The morphological studies on M2/t(8; 21) acute nonlymphocytic leukemia.

作者信息

Chen F J, Yang A D, Fei H B

机构信息

Research Institute of Hematology, Xiehe Hospital, Tongji Medical University, Wuhan.

出版信息

J Tongji Med Univ. 1994;14(1):38-41. doi: 10.1007/BF02888056.

Abstract

Bone marrow studies including morphological, morphometrical and ultrastructural aspects were performed in 35 patients with M2/t(8; 21) and 23 patients with M2/NN. It was found that M2/t(8; 21) patients had higher cellularity in bone marrow. Type (II) myeloblast cells were predominant among myeloblasts. Deformation of nuclei, nucleocytoplasmic asynchronism and dysmegakaryocytopoiesis were more evident in M2/t(8; 21) than in M2/NN patients.

摘要

对35例M2/t(8; 21)患者和23例M2/NN患者进行了骨髓研究,包括形态学、形态计量学和超微结构方面。发现M2/t(8; 21)患者的骨髓细胞密度更高。在原始粒细胞中,(II)型原始粒细胞占主导。与M2/NN患者相比,M2/t(8; 21)患者的细胞核变形、核质不同步和巨核细胞生成异常更为明显。

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