D'Antonio L L, Wigley T L, Zimmerman G J
School of Medicine, Department of Surgery, Loma Linda University, Calif.
Laryngoscope. 1995 Mar;105(3 Pt 1):256-62. doi: 10.1288/00005537-199503000-00007.
Laryngeal/voice function was evaluated in six patients with unilateral true vocal fold paralysis following treatment with Teflon injection (TEF) compared to six patients treated with thyroplasty type I (THY). Auditory perceptual, aerodynamic, and endoscopic assessments were conducted. Three judges rated nine voice characteristics. Aerodynamic measures included estimated subglottal pressure, airflow, and laryngeal resistance. Two judges rated laryngeal characteristics from flexible fiberoptic assessment. The THY group had significantly better voice quality and better quantitative aerodynamic findings compared to the TEF group. The TEF group also was more likely to have an irregular vocal fold edge, an irregular glottal closure pattern, a higher occurrence of hyperfunction and hypertrophy of the false vocal folds, edema, and erythema of the paralyzed folds. Results suggest that THY was associated with more favorable measures of laryngeal/voice function than TEF. It is likely that the poorer perceptual, aerodynamic, and endoscopic findings associated with TEF injection may be due to violation of the true vocal fold cover, particularly increased true vocal fold mass and stiffness.
对6例接受聚四氟乙烯注射（TEF）治疗的单侧真性声带麻痹患者与6例接受Ⅰ型甲状成形术（THY）治疗的患者的喉/嗓音功能进行了评估。进行了听觉感知、空气动力学和内镜评估。三名评判员对九种嗓音特征进行评分。空气动力学测量包括估计的声门下压力、气流和喉阻力。两名评判员根据可弯曲纤维喉镜评估对喉部特征进行评分。与TEF组相比，THY组的嗓音质量明显更好，空气动力学定量结果也更好。TEF组也更有可能出现声带边缘不规则、声门闭合模式不规则、假声带功能亢进和肥大的发生率更高、麻痹声带水肿和红斑。结果表明，与TEF相比，THY与更有利的喉/嗓音功能指标相关。与TEF注射相关的较差的感知、空气动力学和内镜检查结果可能是由于真性声带覆盖层受到破坏，特别是真性声带质量和硬度增加。
