Blanch P, Gómez-Hospital J A, Serrano M, Lozano C, Girona J, Casaldáliga J
Unidad de Cardiología Pediátrica, Hospital Infantil Valle Hebrón, Barcelona.
Rev Esp Cardiol. 1995 Jan;48(1):42-8.
The incidence of late complications after a physiological correction of the patients with transposition of the great arteries (D-TGA) is very significant, due to the alternative operation of the arterial switch.
We studied 125 patients with D-TGA, treated with Senning surgical correction between december of 1978 and november of 1990. Surgery was performed at a mean age of 11.7 months (from 7 days to 11.2 years), and the postoperative mean follow-up was 7.3 years (from 1.4 to 14.3 years). We analyzed their evolutive clinical condition, ECG, Holter and echocardiogram-Doppler. Four groups were defined: A) Simple, 48.8%. B) Associated with ventricular septal defect, 22.4%. C) With pulmonary stenosis, 15.2%. D) Both anomalies, 13.6%.
Sixteen children died (12.8%), 11 of them on the postoperative period. The remaining 5 patients died, at a mean time of 34.3 months after surgery, because they were in cardiac failure. All of patients had enlargement of right ventricle and tricuspid regurgitation was observed in 39 children. There were 3 reoperations. Atrioventricular block was observed in 5.7% of the patients, 33.3% were not in sinus rhythm, 6.6% had atrial flutter-fibrillation, sinus node dysfunction was observed in 24.7%, and five permanent pacemakers were implanted (4.7%).
The later mortality is not high, and the clinical outcome is good, but the frequent rhythm disturbances and enlargement of the right ventricle could let us conclude the hypothesis that anatomical correction is an optimal alternative procedure.
由于大动脉转位(D-TGA)患者采用动脉调转术这一替代手术,其晚期并发症的发生率非常高。
我们研究了1978年12月至1990年11月期间接受森宁手术矫正的125例D-TGA患者。手术平均年龄为11.7个月(7天至11.2岁),术后平均随访时间为7.3年(1.4至14.3年)。我们分析了他们的临床演变情况、心电图、动态心电图和超声心动图-多普勒检查结果。分为四组:A)单纯型,48.8%。B)合并室间隔缺损,22.4%。C)合并肺动脉狭窄,15.2%。D)两种异常均有,13.6%。
16名儿童死亡(12.8%),其中11名在术后死亡。其余5例患者在术后平均34.3个月时因心力衰竭死亡。所有患者右心室均增大,39例儿童观察到三尖瓣反流。有3例再次手术。5.7%的患者观察到房室传导阻滞,33.3%的患者非窦性心律,6.6%的患者有心房扑动-颤动,24.7%的患者观察到窦房结功能障碍,植入了5个永久性起搏器(4.7%)。
晚期死亡率不高,临床结果良好,但频繁的节律紊乱和右心室增大使我们可以得出解剖矫正术是一种最佳替代手术的假设。