Suppr超能文献

医生是否应该在儿童期进行干预以预防成人高血压?

Should physicians intervene during childhood to prevent adult hypertension?

作者信息

Ellison R C

机构信息

Boston University School of Medicine, Massachusetts.

出版信息

Schweiz Med Wochenschr. 1995 Feb 18;125(7):264-9.

PMID:7878404
Abstract

Hypertension in adulthood is a major health problem, and drug treatment of hypertension is expensive and has adverse side effects. By the time that treatment of hypertension begins during adulthood, considerable damage may have already been done to the arterial system, to the left ventricle, and perhaps to other organs. Thus, from several points of view, prevention would be preferable to treatment. We can consider both the high-risk approach and the population approach during childhood for the prevention of adult hypertension. In the high-risk approach, we must first identify individual children who are at high risk and then intervene among them on a one-on-one basis. Identifying the future hypertensive is difficult because of large day-to-day variability in blood pressure during childhood, poor tracking of blood pressure from childhood to adulthood, and the current lack of good gene markers for hypertension. With the population approach, we do not need to identify high-risk children, but take steps among all children that will help prevent the development of hypertension in the entire population. At the present time, our best approach for the prevention of adult hypertension seems to be the population approach. We should make the usual diet, for all children, lower in sodium and fat and higher in potassium and calcium. This is effected by increasing their intake of vegetables, fruits, and whole grains, which should become the basis of the diet, rather than high-fat meat and dairy products. Further, increasing strenuous physical activity in our children may help prevent the development of obesity. Finally, preventing the initiation of cigarette smoking and excess alcohol consumption will help in our efforts to prevent hypertension and its sequelae in the next generation of adults.

摘要

成年期高血压是一个主要的健康问题,高血压的药物治疗费用高昂且有不良副作用。在成年期开始治疗高血压时,动脉系统、左心室以及可能其他器官可能已经受到了相当大的损害。因此,从多个角度来看,预防优于治疗。我们可以在儿童期考虑采用高危个体预防法和群体预防法来预防成年期高血压。在高危个体预防法中,我们必须首先识别出高危儿童个体,然后对他们进行一对一干预。由于儿童期血压的日常波动较大、从儿童期到成年期血压追踪不佳以及目前缺乏良好的高血压基因标志物,识别未来的高血压患者很困难。采用群体预防法时,我们不需要识别高危儿童,而是在所有儿童中采取措施,这将有助于预防整个人群高血压的发生。目前,我们预防成年期高血压的最佳方法似乎是群体预防法。我们应该让所有儿童的日常饮食减少钠和脂肪的摄入,增加钾和钙的摄入。这可以通过增加蔬菜、水果和全谷物的摄入量来实现,它们应该成为饮食的基础,而不是高脂肪的肉类和奶制品。此外,增加儿童的剧烈体育活动可能有助于预防肥胖。最后,防止儿童开始吸烟和过度饮酒将有助于我们预防下一代成年人高血压及其后遗症。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验