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[对规则音调之间极短间隔的失匹配负波(MMN)]

[Mismatch negativity (MMN) to very short interval between regular tones].

作者信息

Jiang D M, Paavilainen P, Lavikainen J, Reinikainen K, Näätänen R

机构信息

Shanghai Brain Research Institute, Chinese Academy of Sciences, Shanghai.

出版信息

Sheng Li Xue Bao. 1994 Dec;46(6):561-7.

PMID:7878484
Abstract

The Mismatch Negativity (MMN) component of the auditory event-related potential (AERP) is elicited by infrequent, physically "deviant" stimuli in a sequence of frequent homogeneous stimuli ("standard"), for instance, by a change in frequency, intensity or duration etc. When the inter-stimulus interval (ISI) of tone pips was occasionally shortened either to 300, 150, 75, 60 and 52 ms from regular ISI 600 ms, which resulted in the elicitation of MMN. The amplitude of MMN elicited by occasional shorter ISI was not reduced as a function of ISI shortening. This indicates that the MMN is not just due to activation of new afferent elements by deviant stimulus. Thus, by no means the elicitation of the MMN can be explained on the basis of the refractoriness.

摘要

听觉事件相关电位(AERP)的失配负波(MMN)成分是由一系列频繁出现的同质刺激(“标准刺激”)中偶尔出现的、物理上“异常”的刺激引发的,例如频率、强度或持续时间等的变化。当短纯音的刺激间隔(ISI)偶尔从常规的600毫秒缩短至300、150、75、60和52毫秒时,会引发MMN。偶尔缩短ISI所引发的MMN的波幅并不会随着ISI的缩短而降低。这表明MMN不仅仅是由异常刺激激活新的传入神经元素所致。因此,绝不能基于不应期来解释MMN的引发。

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