Vascularized bone marrow transplantation in rats: evidence for amplification of hematolymphoid chimerism and freedom from graft-versus-host reaction.
作者信息
Llull R, Murase N, Ye Q, Manez R, Demetris A J, Fournier V, Starzl T E
机构信息
Pittsburgh Transplantation Institute, University of Pittsburgh, PA.
出版信息
Transplant Proc. 1995 Feb;27(1):164-5.
Abstract
摘要
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Optimizing chimerism level through bone marrow transplantation and irradiation to induce long-term tolerance to composite tissue allotransplantation.通过骨髓移植和照射来优化嵌合体水平，以诱导对复合组织同种异体移植的长期耐受。
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Chimerism, graft-vs-host disease, rejection, and their association with reciprocal donor-host immune reactions after cell, organ, and composite tissue transplantation.嵌合体、移植物抗宿主病、排斥反应，以及它们与细胞、器官和复合组织移植后供体-宿主相互免疫反应的关联。
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Mesenchymal stem cells enhance the induction of mixed chimerism and tolerance to rat hind-limb allografts after bone marrow transplantation.间充质干细胞增强骨髓移植后大鼠后肢同种异体移植物混合嵌合体的诱导和耐受。
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Inhibition of alloreactivity in the popliteal lymph node assay by malononitrilamides.丙二腈酰胺在腘淋巴结试验中对同种异体反应性的抑制作用。
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Development of stable mixed T cell chimerism and transplantation tolerance without immune modulation in recipients of vascularized bone marrow allografts.
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The need for inducing tolerance in vascularized composite allotransplantation.在血管化复合组织异体移植中诱导免疫耐受的必要性。
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Immunocytes of composite tissue allografts express elevated levels of TGF beta mRNA and protein during chronic rejection.在慢性排斥反应期间，复合组织同种异体移植物的免疫细胞表达升高水平的转化生长因子β信使核糖核酸和蛋白质。
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本文引用的文献
1
Composite tissue (limb) allografts in rats. III. Development of donor-host lymphoid chimeras in long-term survivors.
Transplantation. 1986 Jan;41(1):39-43.
2
Vascularized bone marrow transplantation (VBMT): induction of stable mixed T-cell chimerism and transplantation tolerance in unmodified recipients.
Transplant Proc. 1991 Feb;23(1 Pt 1):739-40.
3
Cell migration, chimerism, and graft acceptance.细胞迁移、嵌合现象与移植物接受
Lancet. 1992 Jun 27;339(8809):1579-82. doi: 10.1016/0140-6736(92)91840-5.
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