McDonough S P, Stull C L, Osburn B I
Department of Pathology, School of Veterinary Medicine, University of California, Davis 95616.
Am J Vet Res. 1994 Nov;55(11):1516-20.
Observations were made on development of diarrhea in special-fed calves (n = 460) on 8 commercial facilities during 2 successive 16-week production cycles at weeks 0, 2, 4, 8, 12, and 16. A total of 23% were affected, with peak number of calves with diarrhea observed at week 0. Suspected enteropathogens were identified in 86% of these calves, most commonly cryptosporidia, coronavirus, and rotavirus. Identified potential zoonotic pathogens included Giardia and Salmonella spp and verotoxigenic Escherichia coli. Noncytopathic bovine viral diarrhea virus was isolated from 6 calves that had repeated bouts of illness. Only 22% of calves entering the veal facilities had adequate transfer of passive immunity. At week 0, serum IgG concentration in calves that subsequently died or had diarrhea was lower (P < 0.001) than that in healthy calves. All calves that died (n = 6) during the first 4 weeks of production had complete failure of transfer of passive immunity.
在8个商业养殖场，对460头特殊饲养的犊牛在连续两个16周的生产周期内的第0、2、4、8、12和16周的腹泻情况进行了观察。共有23%的犊牛受到影响，腹泻犊牛数量在第0周达到峰值。在这些犊牛中，86%检测出疑似肠道病原体，最常见的是隐孢子虫、冠状病毒和轮状病毒。鉴定出的潜在人畜共患病原体包括贾第虫、沙门氏菌属和产志贺毒素大肠杆菌。从6头反复发病的犊牛中分离出非细胞病变型牛病毒性腹泻病毒。进入小牛肉养殖场的犊牛中，只有22%的犊牛被动免疫转移充分。在第0周，随后死亡或腹泻的犊牛血清IgG浓度低于健康犊牛（P < 0.001）。在生产的前4周内死亡的所有犊牛（n = 6）被动免疫转移均完全失败。
