Thompson R C Andrew, Palmer Carlysle S, O'Handley Ryan
WHO Collaborating Centre for the Molecular Epidemiology of Parasitic Infections, School of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, WA 6150, Australia.
Vet J. 2008 Jul;177(1):18-25. doi: 10.1016/j.tvjl.2007.09.022. Epub 2007 Nov 26.
Giardia and Cryptosporidium are common enteric parasites of domestic animals, particularly dogs, cats and livestock. Their occurrence is of potential significance from both clinical and public health perspectives yet, until recently, confusion over the taxonomy of these organisms prevented a clear understanding of the epidemiology of infections with both Giardia and Cryptosporidium. The recent application of molecular epidemiological tools has helped to resolve taxonomic issues, allowing cycles of transmission to be determined. In addition, advances have been made in elucidating mechanisms associated with pathogenesis, whereas only limited progress has been achieved in the areas of chemotherapy and prophylaxis.
贾第虫和隐孢子虫是家畜常见的肠道寄生虫，尤其是犬、猫和家畜。从临床和公共卫生角度来看，它们的出现都具有潜在意义。然而，直到最近，由于对这些生物体分类学的混淆，阻碍了对贾第虫和隐孢子虫感染流行病学的清晰理解。分子流行病学工具的最新应用有助于解决分类学问题，从而确定传播周期。此外，在阐明与发病机制相关的机制方面也取得了进展，而在化疗和预防领域仅取得了有限的进展。
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