Jitsuiki J, Ochi M, Ikuta Y
Department of Orthopaedic Surgery, Hiroshima University School of Medicine, Japan.
Arthroscopy. 1994 Dec;10(6):659-66. doi: 10.1016/s0749-8063(05)80065-9.
This report describes the methods and effectiveness of interpositional free synovial autografts (IPFSAs) in promoting the healing of lesions in the avascular portion of the knee joint meniscus in rabbits. Thirty-four specimens were divided into two groups: 17 in the study group and 17 in the control group. The medial meniscus of the left knee joint was excised in each rabbit, and an artificial longitudinal tear was created in the avascular zone of the meniscus. In the study group, an IPFSA was sewn into the tear with a single horizontal suture. In the control group, the tear was repaired without synovium in the same manner. The menisci were then implanted into the right knee joint in the respective animals. At intervals the animals were killed, and the menisci were examined grossly and microscopically. Three menisci were eliminated because they had become attached to the synovial wall. In the study group, the lesion completely healed by 4 weeks, except for one. The menisci in the control group never completely healed, particularly at the deeper levels of the lesion. At 8-16 weeks, autolysis of the specimens made microscopic examination difficult and unreliable in both groups. Based on these results, it has been concluded that an IPFSA can promote the healing process in the avascular zone of a torn meniscus in rabbits and that systemic vascularity to the synovium or the meniscus is not essential for healing to occur.
本报告描述了间置游离自体滑膜移植（IPFSA）促进兔膝关节半月板无血管区损伤愈合的方法及效果。34个标本分为两组：研究组17个，对照组17个。在每只兔的左膝关节切除内侧半月板，并在半月板的无血管区制造一个人工纵向撕裂。研究组用单水平缝线将IPFSA缝入撕裂处。对照组以同样方式修复撕裂处，但不植入滑膜。然后将半月板分别植入相应动物的右膝关节。定期处死动物，对半月板进行大体和显微镜检查。有3个半月板因附着于滑膜壁而被剔除。研究组中，除1个外，损伤在4周时完全愈合。对照组的半月板从未完全愈合，尤其是在损伤较深的部位。在8 - 16周时，两组标本的自溶使显微镜检查变得困难且不可靠。基于这些结果，得出结论：IPFSA可促进兔撕裂半月板无血管区的愈合过程，并且滑膜或半月板的全身血管供应对于愈合的发生并非必不可少。
