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[德国高血醇汽车驾驶员中CDT(缺糖转铁蛋白)及其他酒精问题指标的流行病学研究]

[Epidemiologic study of CDT (carbohydrate-deficient transferrin) and other indicators of alcohol problems in high blood alcohol German automobile drivers].

作者信息

Iffland R, Grassnack F

机构信息

Institut für Rechtsmedizin, Universität zu Köln.

出版信息

Blutalkohol. 1995 Jan;32(1):26-41.

PMID:7880487
Abstract

Alcoholism indicators like CDT, GGT, methanol and acetone + isopropanol were measured in blood samples of male German alcoholized car drivers who were at least 18 years old and had a minimum BAC of 0.80 g/kg (per mille). The investigation of 534 cases reflects German conditions. The study proves that a BAC of 1.60 g/kg (per mille) is no appropriate criterion for the assumption of alcohol problems. Alcohol problems appeared significantly more often in cases where BAC levels were 2.0 g/kg (per mille) or higher. It is thought that a total of 20 to 25% of the alcoholized drivers have serious alcohol problems. Amongst those the proportions were as follows: 8% amongst the under 30s and one third amongst tho over 30s. 40% of all drivers with alcohol problems had BACs below 1.6 g/kg (per mille) during the offence. CDT has proved to be a valuable addition to the other indicators when detecting alcoholism in DWI drivers.

摘要

在至少18岁、最低血液酒精浓度(BAC)为0.80克/千克(千分比)的德国男性酗酒汽车司机的血液样本中,检测了如平均红细胞体积(MCV)、γ-谷氨酰转肽酶(GGT)、甲醇以及丙酮+异丙醇等酗酒指标。对534个案例的调查反映了德国的情况。该研究证明,1.60克/千克(千分比)的血液酒精浓度并非判断酗酒问题的合适标准。在血液酒精浓度水平为2.0克/千克(千分比)或更高的案例中,酗酒问题出现的频率明显更高。据认为,总共20%至25%的酗酒司机存在严重的酗酒问题。其中,各年龄段的比例如下:30岁以下的占8%,30岁以上的占三分之一。所有有酗酒问题的司机中,40%在违法时血液酒精浓度低于1.6克/千克(千分比)。在检测酒驾司机的酗酒情况时,平均红细胞体积已被证明是其他指标的一项有价值的补充。 (注:原文中CDT一般指平均红细胞体积,英文全称为Mean Corpuscular Volume ,这里按照常见医学翻译进行了补充翻译,若原文有特殊含义,请根据实际情况调整)

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