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单纯性肝囊肿的经皮酒精硬化治疗。意大利多中心调查结果。

Percutaneous alcohol sclerotherapy of simple hepatic cysts. Results from a multicentre survey in Italy.

作者信息

Montorsi M, Torzilli G, Fumagalli U, Bona S, Rostai R, De Simone M, Rovati V, Mosca F, Filice C

机构信息

Institute of General Surgery, University of Milano-Ospedale Maggiore Policlinico, I.R.C.C.S.-Milano, Italy.

出版信息

HPB Surg. 1994;8(2):89-94. doi: 10.1155/1994/10372.

Abstract

The increased use of Ultrasonography (US) has led to increased detection of simple hepatic cysts. For symptomatic cysts treatment is necessary. Until some years ago surgery was the only therapy. We have treated a large number of patients with Percutaneous Alcohol Sclerotherapy (PAS) and evaluated retrospectively the efficacy of this approach. Data on 21 patients with symptomatic simple hepatic cysts were reviewed retrospectively. Cysts had a mean diameter of 9 cm (range: 7-15 cm). PAS was always performed under local anesthesia and US guidance. 25% of the volume was replaced with 95% ethanol and then completely aspirated after 20-30 minutes. No complications or deaths occurred. In all patients symptoms disappeared after treatment. In 15 out of 21 cases there was no evidence of residual cyst on US, computed tomography (CT) or magnetic resonance (MRI). In 6 patients with shorter follow-up, cysts showed a mean reduction in diameter of 50%. The mean follow-up was 18 months (range 6-60 months). We conclude that PAS is easy with low risk for the patients and with good long-term results; it should therefore become the procedure of choice for simple hepatic cysts.

摘要

超声检查(US)使用的增加导致单纯性肝囊肿的检出率上升。对于有症状的囊肿,治疗是必要的。直到几年前,手术还是唯一的治疗方法。我们用经皮酒精硬化疗法(PAS)治疗了大量患者,并对这种方法的疗效进行了回顾性评估。回顾性分析了21例有症状的单纯性肝囊肿患者的数据。囊肿平均直径为9厘米(范围:7 - 15厘米)。PAS总是在局部麻醉和超声引导下进行。用95%乙醇置换25%的囊肿体积,然后在20 - 30分钟后完全抽吸。未发生并发症或死亡。所有患者治疗后症状消失。21例中有15例在超声、计算机断层扫描(CT)或磁共振成像(MRI)上没有残余囊肿的迹象。在随访时间较短的6例患者中,囊肿平均直径缩小了50%。平均随访时间为18个月(范围6 - 60个月)。我们得出结论,PAS操作简便,对患者风险低,长期效果良好;因此,它应该成为单纯性肝囊肿的首选治疗方法。

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