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粗糖增强颗粒从肺部的转运。

Enhanced translocation of particles from lungs by jaggery.

作者信息

Sahu A P, Saxena A K

机构信息

Industrial Toxicology Research Centre, Lucknow, India.

出版信息

Environ Health Perspect. 1994 Oct;102 Suppl 5(Suppl 5):211-4. doi: 10.1289/ehp.94102s5211.

DOI:10.1289/ehp.94102s5211
PMID:7882934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1567304/
Abstract

Because industrial workers in dusty or smoky environments seemed to experience no discomfort if they consumed the sugar cane product jaggery, experimental studies were undertaken to observe the effects of jaggery on dust-exposed rats. Rats with and without a single intratracheal instillation of coal dust (50 mg/rat) were orally gavaged with jaggery (0.5 g/rat, 5 days/week for 90 days). The enhanced translocation of coal particles from lungs to tracheobronchial lymph nodes was observed in jaggery-treated rats. Moreover, the jaggery reduced the coal-induced histological lesions and hydroxyproline contents of lungs. The lesions induced in omental tissue and regional lymph nodes by a single intraperitoneal injection of 50 mg each of coal and silica dust were modified by jaggery (0.5 g/rat, 5 days/week for 30 days). These findings along with the preventive action of jaggery on smoke-induced lung lesions suggest the potential of jaggery as protective agent for workers in dusty and smoky environments.

摘要

由于在多尘或烟雾弥漫环境中的产业工人如果食用甘蔗制品粗糖似乎不会感到不适，因此开展了实验研究来观察粗糖对接触粉尘大鼠的影响。对有或没有单次气管内注入煤尘（50毫克/只大鼠）的大鼠经口灌胃粗糖（0.5克/只大鼠，每周5天，共90天）。在经粗糖处理的大鼠中观察到煤颗粒从肺向气管支气管淋巴结的转运增强。此外，粗糖减少了煤引起的肺部组织学损伤和羟脯氨酸含量。单次腹腔注射各50毫克煤尘和二氧化硅粉尘在网膜组织和局部淋巴结中诱导产生的损伤，经粗糖（0.5克/只大鼠，每周5天，共30天）处理后得到改善。这些发现以及粗糖对烟雾诱导的肺部损伤的预防作用表明，粗糖有可能成为多尘和烟雾弥漫环境中工人的保护剂。

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The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid.对含有少量这种亚氨基酸的组织和蛋白质样品中羟脯氨酸的测定。
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Wound healing in lysine deficiency.赖氨酸缺乏时的伤口愈合
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Lectins as cell recognition molecules.作为细胞识别分子的凝集素。
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