雷尼替丁对家兔中格列本脲和甲苯磺丁脲降血糖活性的影响。
Influence of ranitidine on the hypoglycaemic activity of glibenclamide and tolbutamide in rabbits.
作者信息
Krishnaiah Y S, Satyanarayana S, Visweswaram D
机构信息
Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam.
出版信息
Indian J Physiol Pharmacol. 1994 Oct;38(4):316-8.
PMID:7883304
Abstract
The influence of ranitidine on the hypoglycaemic activity of glibenclamide and tolbutamide was studied in rabbits. Ranitidine treatment (15 mg/kg, po, twice daily for one week) enhanced the hypoglycaemic activity of glibenclamide (40 micrograms/kg, po) while it has not altered either the hypoglycaemic activity or pharmacokinetics of tolbutamide (40 mg/kg, po) in rabbits.
摘要
在兔子身上研究了雷尼替丁对格列本脲和甲苯磺丁脲降血糖活性的影响。雷尼替丁治疗（15毫克/千克，口服，每日两次，持续一周）增强了格列本脲（40微克/千克，口服）的降血糖活性，而对兔子甲苯磺丁脲（40毫克/千克，口服）的降血糖活性或药代动力学均无影响。
Zotero 插件