Influence of ranitidine on the hypoglycaemic activity of glibenclamide and tolbutamide in rabbits.
作者信息
Krishnaiah Y S, Satyanarayana S, Visweswaram D
机构信息
Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam.
出版信息
Indian J Physiol Pharmacol. 1994 Oct;38(4):316-8.
PMID:7883304
Abstract
The influence of ranitidine on the hypoglycaemic activity of glibenclamide and tolbutamide was studied in rabbits. Ranitidine treatment (15 mg/kg, po, twice daily for one week) enhanced the hypoglycaemic activity of glibenclamide (40 micrograms/kg, po) while it has not altered either the hypoglycaemic activity or pharmacokinetics of tolbutamide (40 mg/kg, po) in rabbits.
摘要
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