• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

暴露于极端生理条件下的免疫系统。

The immune system during exposure to extreme physiologic conditions.

作者信息

Pedersen B K, Kappel M, Klokker M, Nielsen H B, Secher N H

机构信息

Copenhagen Muscle Research Centre, Department of Infectious Diseases, University of Copenhagen, Denmark.

出版信息

Int J Sports Med. 1994 Oct;15 Suppl 3:S116-21. doi: 10.1055/s-2007-1021125.

DOI:10.1055/s-2007-1021125
PMID:7883392
Abstract

It is not clear how the immune system is modulated in response to physical stress (e.g. trauma, surgery, burn and sepsis). In order to better understand the stress-induced immune changes, effects of isolated stressors are evaluated. Human experiments include hypoxia, head-up tilt, hyperthermina and exercise, which influence all lymphocyte subtypes and especially so the natural killer (NK) cells. In essence, the immune response is enhanced even by light physical stress, but suppressed after prolonged, intense stress.

摘要

目前尚不清楚免疫系统如何响应身体应激(如创伤、手术、烧伤和败血症)进行调节。为了更好地理解应激诱导的免疫变化,我们评估了单独应激源的影响。人体实验包括缺氧、头高位倾斜、高温和运动,这些都会影响所有淋巴细胞亚群,尤其是自然杀伤(NK)细胞。本质上,即使是轻度身体应激也会增强免疫反应,但在长期强烈应激后会受到抑制。

相似文献

1
The immune system during exposure to extreme physiologic conditions.暴露于极端生理条件下的免疫系统。
Int J Sports Med. 1994 Oct;15 Suppl 3:S116-21. doi: 10.1055/s-2007-1021125.
2
Perinatal stress influences lymphocyte subset counts in neonates. The generation R study.围产期应激影响新生儿淋巴细胞亚群计数。 Generation R研究。
Pediatr Res. 2008 Mar;63(3):292-8. doi: 10.1203/PDR.0b013e318163a29f.
3
Effects of combined stress during intense training on cellular immunity, hormones and respiratory infections.高强度训练期间复合应激对细胞免疫、激素及呼吸道感染的影响
Neuroimmunomodulation. 2005;12(3):164-72. doi: 10.1159/000084849.
4
Exercise, infection, and immunity.运动、感染与免疫。
Int J Sports Med. 1994 Oct;15 Suppl 3:S131-41. doi: 10.1055/s-2007-1021128.
5
Human natural killer cell subsets and acute exercise: a brief review.人类自然杀伤细胞亚群与急性运动:简要综述。
Exerc Immunol Rev. 2008;14:8-23.
6
Exercise, stress and mucosal immunity in elite swimmers.
Adv Exp Med Biol. 1995;371A:571-4. doi: 10.1007/978-1-4615-1941-6_120.
7
Exercise under hot conditions: a major threat to the immune response?炎热条件下的运动:对免疫反应的重大威胁?
J Sports Med Phys Fitness. 2002 Sep;42(3):368-78.
8
Modulation of human natural killer cell activity by exposure to uncontrollable stress.
Brain Behav Immun. 1992 Jun;6(2):141-56. doi: 10.1016/0889-1591(92)90014-f.
9
Acute stress reduces intraparenchymal lung natural killer cells via beta-adrenergic stimulation.急性应激通过β-肾上腺素能刺激减少肺实质内的自然杀伤细胞。
Clin Exp Immunol. 2005 Jan;139(1):25-34. doi: 10.1111/j.1365-2249.2005.02672.x.
10
Immune suppression while awaiting surgery and following it: dissociations between plasma cytokine levels, their induced production, and NK cell cytotoxicity.等待手术期间及术后的免疫抑制:血浆细胞因子水平、其诱导产生及自然杀伤细胞细胞毒性之间的分离
Brain Behav Immun. 2007 May;21(4):503-13. doi: 10.1016/j.bbi.2006.12.006. Epub 2007 Feb 12.

引用本文的文献

1
Use of K12 in supporting the mucosal immune function of active young subjects: A randomised double-blind study.K12 在支持活跃年轻受试者黏膜免疫功能中的应用:一项随机、双盲研究。
Front Immunol. 2023 Mar 2;14:1129060. doi: 10.3389/fimmu.2023.1129060. eCollection 2023.
2
Acute and chronic effects of physical exercise on IgA and IgG levels and susceptibility to upper respiratory tract infections: a systematic review and meta-analysis.运动对 IgA 和 IgG 水平及上呼吸道感染易感性的急性和慢性影响:系统评价和荟萃分析。
Pflugers Arch. 2022 Dec;474(12):1221-1248. doi: 10.1007/s00424-022-02760-1. Epub 2022 Oct 17.
3
Cardiac Autonomic and Salivary Responses to a Repeated Training Bout in Elite Swimmers.
精英游泳运动员对重复训练课的心脏自主神经和唾液反应
Sports (Basel). 2016 Feb 24;4(1):13. doi: 10.3390/sports4010013.
4
Oligonol supplementation affects leukocyte and immune cell counts after heat loading in humans.补充低聚原花青素会影响人体在热负荷后白细胞和免疫细胞的计数。
Nutrients. 2014 Jun 24;6(6):2466-77. doi: 10.3390/nu6062466.
5
Trauma-induced systemic inflammatory response versus exercise-induced immunomodulatory effects.创伤诱导的全身炎症反应与运动诱导的免疫调节作用
Sports Med. 2006;36(5):373-84. doi: 10.2165/00007256-200636050-00001.
6
Living high-training low altitude training: effects on mucosal immunity.高住低训:对黏膜免疫的影响
Eur J Appl Physiol. 2005 Jun;94(3):298-304. doi: 10.1007/s00421-005-1317-4. Epub 2005 Mar 12.
7
Lymphocyte responses to maximal exercise: a physiological perspective.淋巴细胞对最大运动的反应:生理学视角
Sports Med. 2003;33(11):853-67. doi: 10.2165/00007256-200333110-00005.
8
Effects of three different types of exercise on blood leukocyte count during and following exercise.三种不同类型的运动对运动期间及运动后血液白细胞计数的影响。
Sao Paulo Med J. 2003 Jan 2;121(1):9-14. doi: 10.1590/s1516-31802003000100003. Epub 2003 Jul 4.
9
Impact of elevated ambient temperatures on the acute immune response to intensive endurance exercise.环境温度升高对高强度耐力运动急性免疫反应的影响。
Eur J Appl Physiol. 2003 May;89(3-4):344-51. doi: 10.1007/s00421-003-0809-3. Epub 2003 Mar 25.
10
Alterations induced by chronic stress in lymphocyte subsets of blood and primary and secondary immune organs of mice.慢性应激对小鼠血液及一级和二级免疫器官中淋巴细胞亚群的影响。
BMC Immunol. 2001;2:7. doi: 10.1186/1471-2172-2-7. Epub 2001 Jul 31.