生长抑素对离体大鼠胰岛中己糖诱导的胰高血糖素分泌抑制作用的调节。
Modulation of the hexose induced suppression of glucagon secretion by somatostatin on isolated pancreatic rat islets.
作者信息
Hahn H J, Ziegler M
出版信息
Acta Biol Med Ger. 1976;35(3-4):439-42.
PMID:788424
Abstract
Somatostatin inhibits in a dose-dependent manner the glucagon secretion in the presence of up to 5 mM glucose, whereas the suppressed glucagon release in the presence of greater than or equal to 10 mM glucose, 10 mM glyceraldehyde, 30 mM fructose or 30 mM mannose is characterized by an increase of hormone release under the influence of somatostatin.
摘要
在存在高达5 mM葡萄糖的情况下，生长抑素以剂量依赖的方式抑制胰高血糖素的分泌，而在存在大于或等于10 mM葡萄糖、10 mM甘油醛、30 mM果糖或30 mM甘露糖的情况下，胰高血糖素释放受到抑制的特征是在生长抑素的影响下激素释放增加。
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