Shih W J, Tasdemiroglu E
Nuclear Medicine and Neurosurgery Service, Department of Veterans Affairs Medical Center, Lexington, Kentucky.
J Nucl Med. 1995 Mar;36(3):470-3.
A man with dementia underwent radionuclide cisternography to establish the diagnosis of communicating hydrocephalus. Technetium-99m-HMPAO brain SPECT images showed marked hypoperfusion of both posterior cerebral cortices and three-dimensional displays that demonstrated perfusion defects at both of the posterior parietotemporal regions. A successful ventriculoperitoneal shunt operation was performed. Five and one-half months later, repeat three-dimensional display showed that the perfusion defects had resolved and a repeat brain SPECT image showed marked improvement of the hypoperfusion. This concurred with postoperative clinical improvement. Technetium-99m-HMPAO brain SPECT, which provides objective documentation of clinical recovery after surgery, could be routinely used to evaluate patients with normal-pressure hydrocephalus.
一名患有痴呆症的男子接受了放射性核素脑池造影以确诊交通性脑积水。锝-99m-HMPAO脑单光子发射计算机断层扫描（SPECT）图像显示双侧大脑后皮质明显灌注不足，三维显示表明双侧顶颞后区域存在灌注缺损。成功进行了脑室腹腔分流手术。五个半月后，重复三维显示表明灌注缺损已消失，重复脑SPECT图像显示灌注不足有明显改善。这与术后临床改善情况相符。锝-99m-HMPAO脑SPECT可为手术后的临床恢复提供客观记录，可常规用于评估正常压力脑积水患者。
