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[全身乳剂。2. 不同制剂方法的应用:百里香精油对稳定性的影响]

[Systemic emulsions. 2. Use of different methods of formulation: the effect of essential oils of thyme on stability].

作者信息

Passet J, Laget J P, Nielloud F, Delonca H

机构信息

Faculté de Pharmacie, Laboratoire de Technique Pharmaceutique Industrielle, Montpellier.

出版信息

J Pharm Belg. 1994 Nov-Dec;49(6):469-78.

PMID:7884636
Abstract

As part of an ongoing investigation on emulsifying techniques, we studied the influence of different essential oils from Thymus vulgaris on emulsion stability. All four chimiotypes tested (geraniol, linalol, carvacrol, and thymol) caused a marked decrease in stability. This instability cannot be explained by a change in the hydrophilic lipophilic balance since the HLBc of the new oil phase (essential oil + paraffine oil) was not significantly different from that of paraffine alone.

摘要

作为正在进行的乳化技术研究的一部分,我们研究了来自普通百里香的不同精油对乳液稳定性的影响。测试的所有四种化学型(香叶醇、芳樟醇、香芹酚和百里酚)都会导致稳定性显著下降。由于新油相(精油+石蜡油)的亲水亲油平衡与单独石蜡的亲水亲油平衡没有显著差异,因此这种不稳定性无法用亲水亲油平衡的变化来解释。

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