Riikonen R, Santavuori P
Department of Child Neurology, Children's Hospital, University of Helsinki, Finland.
Neuropediatrics. 1994 Oct;25(5):227-33. doi: 10.1055/s-2008-1073026.
Forty-four patients aged from one month to 16 years suffering from arterial stroke were carefully studied for any hereditary and acquired risk factors for stroke. No physiologic anticoagulant deficiency or antiphospholipid syndrome was found. Two patients had mitochondrial disease (MELAS). Six patients had migraineous stroke. Migraine and thrombotic disease in the families of the patients were not more prevalent than in the families of the controls. Preceding infections occurred in 34% of the patients, that is, significantly more common than in the age-matched controls. Two children had borreliosis. Repeat strokes occurred particularly in patients with migraine (n = 4) and MELAS (n = 2). The hereditary factors studied here seem to play only a minor role in pediatric patients. Repeated strokes have a varied etiology and are difficult to prevent. Important triggers of strokes are infections.
对44例年龄在1个月至16岁之间的动脉性中风患者进行了仔细研究，以寻找任何中风的遗传和后天危险因素。未发现生理性抗凝剂缺乏或抗磷脂综合征。2例患者患有线粒体疾病（MELAS）。6例患者患有偏头痛性中风。患者家族中的偏头痛和血栓性疾病并不比对照组家族中更常见。34%的患者在中风前发生过感染，也就是说，比年龄匹配的对照组明显更常见。2名儿童患有莱姆病。复发性中风尤其发生在偏头痛患者（n = 4）和MELAS患者（n = 2）中。这里研究的遗传因素在儿科患者中似乎只起次要作用。复发性中风病因多样，难以预防。中风的重要触发因素是感染。
