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[主动脉夹层的外科治疗结果]

[Results of surgical treatment of aortic dissections].

作者信息

Nakayama S, Yamazato A, Hanada M, Sato T, Tamaki S I, Fujioka T, Fudo T, Iwase T, Nakae I, Tanaka T

机构信息

Department of Cardiovascular Surgery, Takeda Hospital, Kyoto, Japan.

出版信息

Nihon Geka Hokan. 1994 May 1;63(3):99-103.

PMID:7887769
Abstract

From January 1989 to September 1993, 59 consecutive patients (35 males and 24 females, mean age 59.6 years old) underwent surgical repair of aortic dissection on the cardiovascular surgical unit at Takeda Hospital. The type of aortic dissection were classified according to Stanford University criteria. Twenty-two patients had acute type A (Ac-A), 10 had chronic type A (Ch-A), 4 had acute type B (Ac-B), and 23 had chronic type B (Ch-B) dissection. Seventeen dissections (29%) in the entire group of 59 cases had ruptured (including cardiac tamponade, pleural effusion and hemoptysis etc.). Ischemia of lower extremity occurred in 7 patients and ischemia of visceral organs in 3 patients. Type A dissection were approached via a median sternotomy and cardiopulmonary bypass with systemic hypothermia. Type B dissections were approached through a left postrolateral thoracotomy. Left heart bypass (left atrial-femoral in 8 cases) and partial cardiopulmonary bypass (femoral-femoral in 12 cases) generally were utilized. Resection of intimal tear and replacement of aorta with vascular grafts (including aortic arch in 19 cases) were performed in most patients and primary closure of the intimal tear was performed in 9 cases using GRF. The over-all operative mortality rate was 36% (8/22) for Ac-A, 20% (2/10) for Ch-A, 25% (1/4) for Ac-B, 22% (5/23) for Ch-B. Main causes of operative death was perioperative brain damage. It is necessary to improve the operative mortality for Ac-A dissections (especially in replacement of aortic arch and arch vessels). Further researches are needed regarding optimal methods of the cerebral protection during reconstruction of aortic arch.

摘要

1989年1月至1993年9月,连续59例患者(35例男性,24例女性,平均年龄59.6岁)在武田医院心血管外科接受主动脉夹层手术修复。主动脉夹层类型根据斯坦福大学标准分类。22例为急性A型(Ac - A),10例为慢性A型(Ch - A),4例为急性B型(Ac - B),23例为慢性B型(Ch - B)夹层。59例患者中17例(29%)夹层破裂(包括心脏压塞、胸腔积液和咯血等)。7例患者出现下肢缺血,3例患者出现内脏器官缺血。A型夹层通过正中胸骨切开术和全身低温下的体外循环进行处理。B型夹层通过左后外侧开胸术进行处理。一般采用左心转流(8例为左心房 - 股动脉转流)和部分体外循环(12例为股动脉 - 股动脉转流)。大多数患者进行内膜撕裂切除并用血管移植物置换主动脉(19例包括主动脉弓),9例使用GRF进行内膜撕裂的一期缝合。Ac - A的总体手术死亡率为36%(8/22),Ch - A为20%(2/10),Ac - B为25%(1/4),Ch - B为22%(5/23)。手术死亡的主要原因是围手术期脑损伤。有必要提高Ac - A夹层的手术死亡率(尤其是在主动脉弓和弓血管置换时)。在主动脉弓重建过程中,关于脑保护的最佳方法需要进一步研究。

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