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溃疡性结肠炎的真实范围?一项放射学、内镜学和组织学研究。

The true extent of ulcerative colitis? A radiological, endoscopic and histological study.

作者信息

Leidenius M, Kellokumpu I, Linden H, Taskinen E

机构信息

Fourth Department of Surgery, Helsinki University Central Hospital, Kasarmikatu, Finland.

出版信息

APMIS. 1994 Dec;102(12):950-5. doi: 10.1111/j.1699-0463.1994.tb05257.x.

DOI:10.1111/j.1699-0463.1994.tb05257.x
PMID:7888162
Abstract

Twenty-six radiological, endoscopic and histological examinations of the large bowel were performed in 25 patients with ulcerative colitis. Extensive colitis was observed in 42% of the radiological, in 38% of the endoscopic, and in 27% of the histological examinations. Agreement as to the extent of the colitis between all three examination methods was reached in 53% of the cases. The endoscopic extent of colitis varied between left-sided and extensive in 41% of the patients during a 7-year median follow-up. The frequent change in the extent of ulcerative colitis and the considerable disagreement between radiography, colonoscopy and histology in evaluating the extent of colitis justify the question, "Does a true, unambiguous extent of colitis really exist?" It is more likely that the extent of colitis is just a function of time and the examination method used.

摘要

对25例溃疡性结肠炎患者进行了26次大肠的放射学、内镜及组织学检查。在42%的放射学检查、38%的内镜检查及27%的组织学检查中观察到广泛性结肠炎。在53%的病例中,所有三种检查方法对结肠炎范围的判断达成一致。在中位7年随访期间,41%的患者内镜下结肠炎范围在左侧性和广泛性之间变化。溃疡性结肠炎范围的频繁变化以及放射学、结肠镜检查和组织学在评估结肠炎范围方面存在的显著分歧,使得“结肠炎是否真的存在一个真实、明确的范围?”这个问题变得合理。结肠炎的范围更有可能只是时间和所使用检查方法的函数。

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Aliment Pharmacol Ther. 2017 Jun;45(12):1481-1492. doi: 10.1111/apt.14063. Epub 2017 Apr 27.