Gliomatosis cerebri at the 17-year-old girl--correlations of histological, CT and MRI appearance.

The neuropathologic findings are compared with CT scans and MRI in the case of gliomatosis cerebri; a 17-year-old girl died 2 years after the first epileptic seizure and the onset of neurologic signs. CT scans showed two poorly defined, hypodense foci: the major one in the left parietal white matter and the minor one in the right frontal white matter. MRI demonstrated on T2 weighted image bilateral diffuse increased signal intensity changes with focal high signal mass in the right frontal white matter and cortex as well as in the left occipito-temporal white matter and cortex. The brain coronal sections showed widespread and diffuse neoplastic infiltration in both cerebral hemispheres: corpus callosum, basal ganglia, brainstem and cerebellum. In the microscopic examination diffuse gliomatous infiltration was found.