del Carpio-O'Donovan R, Korah I, Salazar A, Melançon D
Department of Radiology, Montreal General Hospital, McGill University, Quebec, Canada.
Radiology. 1996 Mar;198(3):831-5. doi: 10.1148/radiology.198.3.8628879.
To characterize gliomatosis cerebri on computed tomographic (CT) and magnetic resonance (MR) images.
MR and CT studies of 22 patients with cerebral gliomatosis were reviewed retrospectively. Tumor was confirmed with autopsy (n=5) or biopsy. Distribution and extent of disease were assessed, and disease progression was followed.
Tumor involved at least two lobes of the brain in all patients, with extension to the corpus callosum in 12, basal ganglia and thalamus in 17, brain stem in three, and cerebellum in two patients. Widespread invasion with hyperintensity was noted on proton-density- and T2-weighted MR images. At CT, areas of hypo- or isoattenuation were noted, and no contrast enhancement occurred. Extent of tumor was greater on MR images than on concurrent CT scans in all patients. The MR findings closely correlated with the autopsy findings.
Gliomatosis cerebri is best detected with MR imaging. The pattern is infiltrative with enlargement of cerebral structures.
在计算机断层扫描（CT）和磁共振（MR）图像上对大脑胶质瘤病进行特征描述。
回顾性分析22例大脑胶质瘤病患者的MR和CT研究资料。通过尸检（n = 5）或活检确诊肿瘤。评估疾病的分布和范围，并随访疾病进展情况。
所有患者的肿瘤均累及至少两个脑叶，12例累及胼胝体，17例累及基底节和丘脑，3例累及脑干，2例累及小脑。在质子密度加权和T2加权MR图像上可见广泛浸润并呈高信号。CT上可见低密度或等密度区，无强化。所有患者的MR图像上肿瘤范围均大于同期CT扫描。MR表现与尸检结果密切相关。
大脑胶质瘤病最好用MR成像检测。其表现为浸润性，伴有脑结构增大。
